BIOSENSOR FOR ALT MEASUREMENT
نویسندگان
چکیده
In this work, an amperometric biosensor to determine ALT, which will be part of a system for simultaneous measurement AST and ALT their ratios, was developed. A platinum disk electrode used as the electrochemical transducer. To form bioselective element, mixture based on glutamate oxidase applied surface universal method measuring activity using developed proposed described. During study, optimal concentrations substrates (α-ketoglutarate - 50 μM, alanine 4 mM) coenzyme (50 mkM PLP) were selected. The analytical characteristics also investigated, namely, sensitivity, linear range, minimum limit determination, selectivity, stability, etc. It shown fundamental possibility measure content in real samples.
منابع مشابه
Nanostructured Optical Photonic Crystal Biosensor for HIV Viral Load Measurement
Detecting and quantifying biomarkers and viruses in biological samples have broad applications in early disease diagnosis and treatment monitoring. We have demonstrated a label-free optical sensing mechanism using nanostructured photonic crystals (PC) to capture and quantify intact viruses (HIV-1) from biologically relevant samples. The nanostructured surface of the PC biosensor resonantly refl...
متن کاملAlgal Biosensor-Based Measurement System for Rapid Toxicity Detection
Microalgae are now widely used as relevant biological indicators in the field of environmental impact studies. Owing to their ubiquity, short life cycles, easiness of culture and high sensitivity to a number of pollutants, these organisms are frequently utilized in ecotoxicological screening of contaminated freshwater (Lewis, 1995). As primary producers, either directly or indirectly, of organi...
متن کاملA quartz crystal biosensor for measurement in liquids.
The detection of anti-human immunodeficiency virus (HIV) antibodies by means of synthetic HIV peptide immobilized on a piezoelectric quartz sensor is demonstrated. The measurement set-up consists of an oscillator circuit, a suitably modified AT-cut thickness-shear-mode quartz crystal with gold electrodes, which is housed in a special reaction vessel, and a computer-controlled frequency counter ...
متن کاملMicro-cantilevered MEMS Biosensor for Detection of Malaria Protozoan Parasites
In this paper, the presented work aims to provide a designed model based on Finite element method for detection of Malaria protozoan parasites. Micro-cantilevers are next generation highly efficient biosensors for detection and prevention of any disease. Here, an E-shaped model for micro cantilevered biosensor is designed using COMSOL Multiphysics specifically for detection of Malaria. Microcan...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Sensorna elektronìka ì mìkrosistemnì tehnologìï
سال: 2022
ISSN: ['2415-3508', '1815-7459']
DOI: https://doi.org/10.18524/1815-7459.2022.1/2.239789